From Mu Valley wiki:

History

In 1503, the Mongyang State attacked and took the northern garrison town of Myedu that guarded the irrigated Mu Valley, an important granary to the Bamar Kingdom of Ava. These attacks culminated in a full-scale invasion in 1524 and the establishment of Shan rule (1527–1555).[6] The Kabaw Valley saw many an invasion by Manipur State to the west, most notably during the reign of Gharib Nawaz (1709–1748), when his army crossed over the Chindwin and the Mu, took Myedu, and reached as far as Sagaing opposite the capital Ava. The tables were turned in 1758 after King Alaungpaya ascended the Burmese throne and invaded Manipur.[7] Descendants from Portuguese captives, the Bayingyi, were taken by King Anaukpetlun after defeating the adventurer Filipe de Brito e Nicote and settled in the area in the 17th century, still keep their Roman Catholic faith. To this day, their ancestry is discernible from their features.[8]